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Read MoreCushing syndrome, also called hypercortisolism, is a condition characterized by a hormone imbalance that may be caused by medication or an underlying condition.
What is Cushing Syndrome (Hypercortisolism)?
Cushing syndrome occurs when the body has too much cortisol, the stress hormone that is essential in regulating blood pressure, blood sugar, and salt levels in the body, reducing inflammation, forming memories, managing respiration and transforming food into energy. Our body releases cortisol in response to stress to increase your heart rate, blood pressure, blood glucose and muscle tension.
There are two main causes of Cushing syndrome. High levels of cortisol could be caused by the use of glucocorticoid medications, which often treat autoimmune disorders like chronic asthma, rheumatoid arthritis, lupus and sarcoidosis.
It can also result from tumors on the pituitary, adrenal glands, lung, pancreas, thyroid or thymus, which trigger excess cortisol production. Pituitary and adrenal tumors are typically benign, while tumors in the lungs, pancreas, thyroid, or thymus are often malignant and stimulate cortisol overproduction. Those most at risk are adults aged 25–50 and individuals taking medications for chronic inflammation.
What are the Symptoms of Cushing's Syndrome?
Symptoms of Cushing’s syndrome vary depending on the person and underlying cause of the condition and can include:
- Diabetes
- Wounds that heal poorly
- Fatigue
- High blood pressure
- Excessive hair growth
- Blurry vision and dizziness
- Easy bruising on the arms and legs
- Purple stretch marks on the abdomen
- Libido changes and erectile dysfunction
- Rapid weight gain in the face, abdomen, neck or chest
How is Cushing Syndrome Diagnosed?
Cushing syndrome can be hard to diagnose, so tracking your symptoms and discussing them with your doctor is key. Diagnosis involves a medical history review, physical exam, and lab tests like urine, saliva, and blood tests. Your doctor may also rule out similar conditions, such as polycystic ovary syndrome PCOS or metabolic syndrome, before confirming Cushing syndrome.
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Cushing Syndrome Treatment Options
Medication Adjustments
If you’re taking a glucocorticoid, your provider may recommend a lower dosage or prescribe a non-glucocorticoid medication to treat your condition. Your doctor may also recommend a medication that reduces cortisol levels.
Chemotherapy and Radiation
If a tumor is causing Cushing syndrome, your doctor may recommend chemotherapy for cancer that has spread to other parts of your body or radiation for inoperable pituitary tumors.
Surgery
If you have a pituitary, adrenal or ectopic tumor, a surgeon may be able to remove it. Once removed, you may have to take cortisol medications to bring your cortisol back to normal levels.
Our Approach to Cushing Syndrome
At Inspira, we provide personalized, comprehensive care tailored to each patient's unique needs. Our endocrinologists develop customized treatment plans based on the cause and severity of your condition, with many cases of Cushing syndrome curable within 18 months.
Beyond treating physical symptoms, we prioritize strong patient relationships and open communication. Our team is here to answer your questions, offer guidance, and provide continuous support, empowering you to take control of your health.
